Jul 6, 2023
Best of Biotech from AZ Bio & Life Sciences to Jellatech
- BRT S04 EP26 (189) 7-2-2023
What We Learned This Week:
- AZ Bio mission to improve life sciences, & make AZ a Top 10 Bioscience state
- Aqualung Therapeutics is treating inflammation in the lungs, get people off ventilators & save lives
- Calviri is working on a Vaccine to PREVENT Cancer, currently largest animal clinical trial
- Anuncia Medical has a Re-Flow product to help drain fluid from the brain, treats Hydrocephalus
- Collagen 2.0 – Innovation to Gelatin & gummies
Seg. 1 – Clips from:
AZ Bio & Life Sciences Innovation w/ Joan Koerber-Walker
- BRT S04 EP10 (172) 3-5-2023
Guest:
Joan
Koerber-Walker
President and CEO,
AZBio - Arizona Bioindustry Association,
Inc.
Chairman, Opportunity Through Entrepreneurship Foundation
LKIN: https://www.linkedin.com/in/joankoerberwalker
Bio:
As President and CEO of AZBio, Joan Koerber-Walker works on behalf of the Arizona Bioscience and Medical Technology Industry to support the growth of the industry, its members and our community on the local and national level. Ms. Koerber-Walker is also a life science investor and has served on the boards of numerous for-profit and non-profit organizations.
In the life science industry, Ms. Koerber-Walker serves as as Arizona’s representative to the State Medical Technology Alliance (SMTA), a consortium of state and regional trade associations representing their local medical technology companies which she chaired in 2015 and represents Arizona as a member of the Council of State Bioscience Associations (CSBA) and the Coalition of State Bioscience Institutes (CSBI).
Active in the entrepreneurial and investment communities, she also serves as Chairman of the Board of the Opportunity Through Entrepreneurship Foundation which provides entrepreneurial education, mentoring and support to at-risk members of the community, on the Board of Advisors to CellTrust, Inc. which provides secure communication technology to the healthcare industry, and as Chairman of CorePurpose, Inc. which she founded in 2002.
Ms. Koerber-Walker has been recognized as Executive of the Year by the Arizona Society of Association Executives, as a “Most Admired Leader” by the Phoenix Business Journal (2015), in the pages of AZ Business Leaders (2013 thru 2020), Most Influential Women in Arizona Business (2014) and is a 2 time National Finalist for the Stevie Award which recognizes the work of women in business.
Her past experience includes two years as the CEO of ASBA (the Arizona Small Business Association), service as a member of the Board of Trustees of the National Small Business Association in Washington D.C., President of the National Speakers Association/Arizona, Chair of the Board of Advisors to Parenting Arizona, the state’s largest child abuse prevention organization, & much more.
AZBio: Supporting Arizona’s Life Science Industry for 19 Years (2003 – 2022)
Learn more about Arizona's bioindustry: www.azbio.org
| Facebook: AZBIO |Twitter: @AZBio @AZBioCEO
We’re part of a movement to create sustainable funding for life science innovation in Arizona.
Learn more at www.AZAdvances.org
MOVING LIFE SCIENCE INNOVATIONS ALONG THE PATH
FROM DISCOVERY TO DEVELOPMENT TO DELIVERY
OUR VISION OF THE FUTURE: Arizona is a top-ten life science state.
OUR MISSION: AZBio supports the needs of Arizona’s growing life science ecosystem.
The Arizona Bioindustry Association (AZBio) is a not-for-profit, 501(c)6 trade association supporting the growth of Arizona’s life science sector.
AZBio Member Organizations in the fields of business, research and education, health care delivery, economic development, government, and other professions involved in the biosciences are the key drivers of the growth of Arizona’s life science sector. As the unified voice of our industry in Arizona, AZBio strives to make Arizona a place where bioscience organizations can grow and succeed.
AZBio works nationally and globally with the Advanced Medical Technology Association (AdvaMed), the Biotechnology Innovation Organization (BIO), the Medical Device Manufacturers Association (MDMA), the Pharmaceutical Research and Manufacturers of America (PhRMA), and leading patient advocacy organizations.
Through these relationships, AZBio has access to information, contacts, resources, cost saving programs, and the global bioscience and medtech community.
Arizona’s bioscience industry is growing rapidly and reached nearly 30,000 jobs spanning 2,160 business establishments in 2018. Industry employment has grown by 15 percent since 2016—twice the growth rate of the nation—with each of the five major subsectors adding jobs during the period. Arizona’s universities conducted nearly $580 million in R&D activities in bioscience-related fields in 2018, fueled in part by steadily increasing NIH awards to Arizona institutions since 2016. Venture capital investments in Arizona bioscience companies increased in 2019, and during the 2016-19 period totaled $349 million. Arizona inventors have been awarded 2,178 bioscience-related patents since 2016, among the second quintile of states in patent activity.
Full Show: HERE
Guest:
Stan
Miele
President & CBO Aqualung
Therapeutics Corp
LKIN: HERE
Stan Miele Bio:
A recognized global executive with success in sales, marketing and P&L leadership in the pharmaceutical/medical device and biotech industries. Mr. Miele was formally the Chief Commercial Officer at bioLytical Laboratories and Sucampo Pharmaceuticals Inc. He was also President of Sucampo Pharma Americas for 6 years. He was instrumental on some key licensing agreements for Sucampo, inclusive of the agreement with Abbott Japan, and also Takeda Pharmaceuticals (now Shire). He is actively part of the team ensuring proper execution of clinical development, manufacturing, licensing, capital funding, alliances, and ensuring Aqualung meets all critical milestones. He will be helping the company move toward accelerating the pipeline/platform technology and moving eNamptor™ toward commercialization.
Aqualung Therapeutics
Aqualung Therapeutics (ALT) is developing multi-pronged strategies to address the development of severe lung inflammation which is essential to the severity and outcomes of acute and chronic lung disorders such as acute lung injury, ventilator-induced lung injury (VILI), idiopathic pulmonary fibrosis, and pulmonary hypertension. Effective FDA-approved drugs are either currently unavailable or extraordinarily modest in their ability to modify disease progression. No drug is currently available that is preventive or curative. Aqualung’s strategies, which include deployment of a human monoclonal antibody which targets a novel inflammatory mediator (nicotinamide phosphoribosyltransferase or NAMPT) will address the unmet need for novel, effective therapies for VILI, IPF, and pulmonary hypertension.
Full Show: HERE
Seg. 2 – Clips from:
Preventing Cancer with a Vaccine w/ Stephen Johnston of Calviri
- BRT S04 EP17 (179) 4-23-2023
Guest:
Stephen
Johnston
Founding CEO, Calviri
Inc.
LKIN: HERE
Bio:
Chief Executive Officer & Chairman of the Board
Stephen Albert Johnston is the inventor of the Calviri’s central technologies. In addition to Calviri, he has been a founder of Eliance, Inc. (Macrogenics), Synbody Biotechnology and HealthTell, Inc. He is Director of the Arizona State University Biodesign Institute’s Center for Innovations in Medicine and Professor in the School of Life Sciences. He has published almost 200 peer-reviewed papers and holds 45 patents. Prior to his appointment at ASU he was Professor and Director of the Center for Biomedical Inventions at UT-Southwestern Medical Center and Professor of Biology and Biomedical Engineering at Duke University. He is a member of the National Academy of Inventors. Dr. Johnston received his B.S. and Ph.D. degrees from the University of Wisconsin.
Calviri Inc.
We are determined to offer humanity a better life, free from cancer. While our goal is hugely ambitious, we are intensely driven to rid the planet of worry from cancer.
Calviri’s mission is to provide affordable products worldwide that will end deaths from cancer. We are a fully integrated healthcare company developing a broad spectrum of vaccines and companion diagnostics that prevent and treat cancer for those either at risk or diagnosed. We focus on using frameshift neoantigens derived from errors in RNA processing to provide pioneering products against cancer. The company is a spin out of the Biodesign Institute, Arizona State University, located in Phoenix, AZ. We have the largest dog vaccine trial in the world underway at three premier veterinary universities. The five-year trial will assess the performance of a preventative cancer vaccine.
Full Show: HERE
ReFlow to Help Treat Hydrocephalus w/ Elsa Abruzzo & Mark Geiger of Anuncia Medical
- BRT S04 EP23 (186) 6-11-2023
Guest: Elsa Chi Abruzzo
RAC, FRAPS – President
Elsa Chi Abruzzo is a medical device executive, entrepreneur, and a founding member of Anuncia, Inc., Alcyone Therapeutics, Arthromeda, Inc. and Cygnus Regulatory. Elsa has a 30+ year successful product development, operations, regulatory, quality, and clinical track record in med tech Industries. Her experience includes leadership positions at Baxter, Cordis JNJ, CryoLife, Percutaneous Valve Technologies, AtriCure, InnerPulse, Merlin MD, Sapheon, and PTS Diagnostics. Elsa earned a BS in engineering from the University of Miami in Coral Gables, FL and is regulatory affairs certified and a Regulatory Affairs Professional Society Fellow, recognized for her leadership in Regulatory and Quality by MDDI.
https://anunciamedical.com/the-anuncia-story/#team
https://www.linkedin.com/in/elsachiabruzzo/
About Anuncia
Conceptualized in 2014 in collaboration with Boston Children’s Hospital and spun out of Alcyone Therapeutics in 2018, Anuncia’s patented portfolio of technologies are intended to provide peace-of-mind through innovation.
Our core ReFlow™ technology uses a simple finger depression of a soft silicone dome located under the patient’s scalp to produce a noninvasive, one-way flush of the patient’s own CSF directed toward the ReFlow™ catheter to restore or increase CSF flow through a non-flowing shunt and potentially avoid emergency surgery.
The name Anuncia comes from Panthera Uncia, the species name of the snow leopard. These animals live in mountainous regions of Asia and have been called by the World Wildlife Foundation “Guardians of the Headwaters” as they roam the headwater areas of the western basins.
The origin of the word hydrocephalus comes from the Greek hudrokephalon, from hudro ‘water’+ kephalē ‘head’. The snow leopard, or Guardian of the Headwaters, is a symbol of Anuncia’s dedication to improve daily quality of life for the millions of underserved patients with hydrocephalus and other CSF disorders, as well as their families, who suffer from the clinical, economic, and emotional burden of repeat revision brain surgery due to VP shunt occlusions.
Full Show: HERE
2nd Half – Clip from:
Cell Based Collagen from Jellatech + BRT 2.2021 - Best of Tech 2021
BRT S02 EP13 (60) 03-28-2021
Guests: Stephanie Michelsen, Co-Founder / CEO Jellatech
Stephanie Michelsen, founder and CEO of Jellatech, aims to use biotechnology to synthesize animal proteins - without killing the animals. This includes collagen and gelatin produced from animal cell lines and cultured in giant bioreactors to be used in food, pharma and cosmetic applications. Jellatech has raised $2.1 million. The Raleigh-based startup CEO lauded, lands on Forbes 30 under 30
https://www.forbes.com/profile/stephanie-michelsen/?sh=1a4e74ed778c
Jellatech is a developer of cutting-edge technologies to produce high quality, pure, animal-free collagen and gelatin. Founded by a group of innovators, dreamers, entrepreneurs and scientists, Jellatech is on a mission to eliminate animals from the food system, making better ingredient products - starting with collagen and gelatin.
Collagen is a by-product of the meat industry (protein in the body). You may be familiar with collagen from seeing it in skin serums, or with its derivative, gelatin, in gummy bears - but it’s likely around you much more than you realize. This ingredient is used in a number of applications such as for food texturizers, vaccine stabilizers, pill capsules, the clarification of wine and beer, and many more.
Today, the only way to source native, functional collagen is to extract it from animals. This is what they are changing at Jellatech. Jellatech makes functional, native collagen - without animals. Cellular agriculture enables one to produce a more sustainable, smarter high quality collagen that breaks the cycle of relying on an inefficient and unethical supply chain of live animals.
Full Show: HERE
AZ Tech Council Shows:
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*Includes Best of AZ Tech Council show from 2/12/2023
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